ABSTRACT
Female sexual dysfunction is a common problem among general population, especially in urogynecological patient, and can lead to a decrease in quality of life and affect martial relationship. This study was compared the effect of surgical methods versus physiotherapy on sexual function in pelvic floor disorder. This randomized controlled trial was performed in Urogynecology clinic since August 2007 to December 2009 on 90 patients aged from 25-55 years with previous delivery, positive history of sexual dysfunction with stage <3 of pelvic organ prolapsed and divided in two groups. Group A [n=45] received standard rectocele repair and prineorrhaphy, group B [n=45] received physiotherapy for eight weeks twice a week [electrical stimulation, Kegel exercises]. The female sexual function index [FSFI] used to evaluate the sexual function in cases before and after intervention. Frequency of variable scores [libido, orgasm, dysparunia] included without disorder, frequently good, sometimes good, very much and extreme were compared between two groups. Libido and arousal were improved in both groups [p=0.007, p=0.001 respectively]. Orgasm and dyspareunia were improved in group B [p=0.001]. Dysparunia was more painful in group A. There was significant difference between two groups [improvement of orgasm and dysparunia in group B] [p=0.001]. It seems that physiotherapy is an appropriate method for treatment of sexual disorder in pelvic floor disorder.
ABSTRACT
Overactive bladder [OAB] is one of the most prevalent diseases of lower urinary system. OAB disease is defined by the Standardization Subcommittee of the International Continence Society as urinary urgency, with or without urge incontinence, usually with frequency and nocturia with no proven infection or other obvious pathology. Treatment with the antimuscarinic agents tolterodine and oxybutynin is the mainstay of therapy for overactive bladder. The study was undertaken to compare the efficacy and side-effects of tolterodine and oxybutynin in a number of Iranian women. This study consisted of two trials and done in Imam Khomeini Hospital in 2009; in one trial, 50 patients with overactive bladder were randomized to 4 weeks of treatment with 2 mg of twice-daily tolterodine, and in the other to 5 mg of three times a day oxybutynin. Urodynamic investigations, Episodes of urge urinary incontinence and adverse events were also evaluated. The results showed a good association between the questionnaire and cystometry data but urodynamic studies showed significant differences in efficacy. Tow groups showed significant improvements in all Symptoms, but The results showed that the two drugs had no significant differences in efficacy. The data obtained by questionnaire indicated that both drugs increased quality of life but there were no significant differences between the two in symptom cure. Dry mouth was the most common side-effect in the two groups but unlike other studies it was higher in the tolterodine group. Therefore, our study did not show any preference between oxybutynin and tolterodine